Scientists reveal cause of weight regain

A recent study suggests that a chemical mechanism in the body may play a role in regaining weight after losing it. Fat cells produce a hormone called "Asprosin," which stimulates feelings of hunger and remains active even after weight loss, creating a "biological memory" of obesity. The study, conducted on mice, found that levels of this hormone stay elevated for weeks following weight loss due to the influence of the inflammation-associated protein TGF-β1, which continues to stimulate Asprosin production. Researchers believe that understanding this mechanism could enhance the development of methods to prevent weight regain, emphasizing the importance of studying epigenetic changes and their effects on fat cells, representing a significant step toward effective obesity treatment.

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