Common painkiller may affect hormones and fertility

Experts have warned that excessive use of ibuprofen, even without a prescription, can lead to temporary changes in hormones and reproductive functions in men and women. An American study showed that taking the maximum daily dose of ibuprofen for six weeks increases luteinizing hormone (LH) levels and decreases testosterone levels, which reflects a reversible state of gonadal insufficiency. Prolonged use of the medication may impair the body's ability to maintain hormonal balance. Clinical studies also indicate that using non-steroidal anti-inflammatory drugs (NSAIDs), such as diclofenac and nabumetone, over ten days can reduce ovulation rates by up to 93% and lead to lower progesterone levels, although hormonal functions tend to return to normal after stopping the medication. Experts advise against regular or long-term use of ibuprofen without medical consultation, especially for women trying to conceive or who are pregnant, as it can affect hormonal balance and fertility. Alternative medications like paracetamol are recommended for daily pain relief, and consulting a doctor is essential if symptoms related to low testosterone or menstrual irregularities appear, to ensure proper diagnosis.

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