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A study presented at ENDO 2026 found that completely removing sucrose from a low-fat diet may negatively affect gut health and metabolism. In a 16-week experiment with mice, those without dietary sugar showed imbalances in gut bacteria, increased inflammation, poor glucose regulation, insulin resistance, and signs of fatty liver disease, despite no weight gain. Researchers suggest that dietary sugar plays a key role in supporting gut microbiota and metabolic health, and future guidelines may focus on balanced nutrition rather than strict sugar elimination.
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