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New York Post
New York Post
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A diagonal crease in the earlobe, known as Frank’s sign, has been increasingly linked to cardiovascular disease and related conditions such as heart attacks, strokes, and peripheral vascular disease. Studies indicate that the presence of this crease, especially when bilateral and deep, may signal higher risk of heart complications independently of other factors. While the exact cause is unclear, some theories suggest a link to tissue changes affecting arteries or genetic factors. However, the crease alone is not a definitive indicator and should be considered alongside other risk factors.
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