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Research indicates that the composition of the gut microbiome influences sepsis outcomes, with certain bacteria associated with increased severity and immune response. A study using mice found that higher levels of specific bacteria, such as Muribaculaceae and Sangeribacter muris, correlated with poorer survival rates and heightened inflammation during infection. Experts suggest maintaining a healthy gut microbiome may help regulate immune responses and reduce the risk of severe sepsis, though further clinical research in humans is needed.
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