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Scientists from Johns Hopkins University have achieved a new understanding of how light-sensitive cells in the retina develop, particularly in the central part of the retina responsible for sharp vision. They identified a precise interaction between a molecule derived from vitamin A and thyroid hormones during fetal development. The results showed that the pattern of cone cells is formed through a series of events that begin with the creation of blue cone cells, some of which later transform into red and green cones due to the breakdown of retinoic acid and stimulation by thyroid hormones. This discovery represents an important step toward developing treatments for vision problems such as macular degeneration and glaucoma, with the potential to use advanced retinal models to replace damaged cells.
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