New vitiligo treatment breakthrough
Japanese researchers have discovered that melanoma cells in vitiligo do not disappear completely; instead, they revert to a more primitive state, leading to a loss of their ability to produce pigment. The study, published in "Nature Communications," explains that changes in the cells' attachment to the membrane and the influence of proteins such as laminin-332 contribute to the decline of pigment cells. By targeting specific pathways with drugs in experiments on mice and human skin, the researchers were able to reactivate the pigment cells and restore pigmentation. This opens up new possibilities for treatments based on reactivating these cells or restoring their normal attachment to the basement membrane, which could significantly alter the way vitiligo is treated.
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