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Reasons for early-onset Alzheimer’s among youth

Reasons for early-onset Alzheimer’s among youth

A recent article discusses the causes and symptoms of early-onset Alzheimer's, which affects individuals under the age of 65 and typically appears between the fourth and fifth decades of life. The article emphasizes that the main causes include definite genetic factors, such as mutations in the (APP), (PSEN1), or (PSEN2) genes, as well as risk genes like (APOE4) that interact with health and environmental factors, such as head injuries and cardiovascular diseases. Its symptoms range from difficulty finding words, behavioral disturbances, and dramatic personality changes, to motor symptoms. The article notes that early diagnosis and testing are challenging in young people, and that disease progression can lead to a final decision for medical-assisted death, as was the case with Rebecca Luna, who died at age 49 after a rapid decline. It points out that the causes involve hereditary and environmental factors that cause brain cell damage and accelerate cerebral aging.

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