Scientists Find Brain Changes Starting at 50
A scientific study has revealed that covert immune change begins in middle age, as small glial immune cells in the brain decrease and are replaced by others exhibiting stronger inflammatory signals. This contributes to understanding how aging affects the development of neurodegenerative diseases such as Alzheimer's. The research showed that this shift typically starts between ages 50 and 75 and reflects changes in the identity and function of immune cells, potentially impacting the blood-brain barrier and increasing the risk of chronic inflammation associated with cognitive decline as we age.
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