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البلاد
Immune shifts after age 110
However, the study indicates that the CD4-type cytotoxic T cells, which increase in the blood after age 110, are not necessarily a cause of longevity or protection against cancer. Instead, they reflect an advanced immune response aimed at monitoring abnormal cells that appear with aging. Their levels have increased significantly in centenarians, and the presence of large groups of identical clones supports the idea that they are continuously targeted against specific immune threats. Although their receptors are similar to those found in patients with lung, breast, and liver cancers, the study does not prove that these cells directly contribute to extending lifespan or preventing cancer. Rather, they suggest the potential for immune system reorganization after the hundred-year mark to better face health challenges associated with aging.
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