Brain replaces immune cells with age
A recent study shows that immune brain cells, known as microglia, are gradually replaced during aging by immune cells originating from the bone marrow. This challenges the previous belief that the brain is an isolated system. The research clarified that these blood-derived cells infiltrate the brain in old age, constituting a significant proportion of microglia, with a protective correlation between the formation of these cells and Alzheimer's disease. It is believed that this discovery revises our understanding of brain aging and opens new avenues for treating neurological diseases by targeting or modifying these external immune cells to improve brain health.
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