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The article highlights a recent study on the molecular classification of prostate cancer using integrated mutational signatures, which account for approximately 85% of cases. The results revealed four mutation patterns associated with rapid tumor progression that appear in about 37% of tumors, aiding in distinguishing between high-risk and low-risk cancers. The aim of this research is to improve the identification of patients requiring early intensive treatment, thereby reducing unnecessary interventions and side effects. It is also expected that future developments will enhance personalized therapeutic options. Although the current findings are limited to research, they represent an important step toward a molecular classification that can help doctors make more accurate treatment decisions in the future.
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