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A recent study has shown that inflammation experienced by the mother during a specific stage of pregnancy may affect the growth of the fetus, particularly in males, and increase the likelihood of traits associated with autism spectrum disorder. The research identified a sensitive period around the twelfth and a half day of pregnancy when the fetus is most susceptible to the effects of the mother's immune system activation. Notably, male fetuses exhibited developmental changes linked to autism, while females continued to develop normally. The researchers explained that changes in the placenta, which help regulate the mother's immune response, might account for the differing impacts of inflammation on the fetuses. This finding enhances the understanding of why autism diagnoses are more common in boys. The results highlight the importance of examining the role of the placenta and the immune system during pregnancy to prevent or reduce the risks of future developmental disorders, with further studies ongoing to deepen scientific understanding.
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