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CBL-514, a drug administered via injection, has demonstrated a new potential approach to treating obesity by encouraging fat cells to destroy themselves instead of simply reducing their size. Two second-phase trials involving 280 participants showed that the medication helped decrease subcutaneous fat, with an average reduction of 12.01% in visceral fat four weeks after the final injection. Studies on mice also indicated that combining CBL-514 with tirzepatide led to greater weight loss, with the effects persisting even after stopping the treatment. However, these results have not yet been reviewed by experts and further larger-scale studies with longer follow-up are needed.
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