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The study reveals that antimicrobial proteins dating back to mammals that lived 160 million years ago have been reconstructed from their extinct ancestors to assess their effectiveness against drug-resistant bacteria. Experiments showed that some of these ancient proteins were more effective at attacking resistant bacteria compared to modern proteins, and a single mutation in their structure was sufficient to significantly boost their potency. These proteins are considered a potential source for developing new treatments to combat antibiotic resistance, although their application as drugs requires further research due to their limited stability within the body.
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