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Ancient proteins challenge resistant bacteria
The study reveals that antimicrobial proteins dating back to mammals that lived 160 million years ago have been reconstructed from their extinct ancestors to assess their effectiveness against drug-resistant bacteria. Experiments showed that some of these ancient proteins were more effective at attacking resistant bacteria compared to modern proteins, and a single mutation in their structure was sufficient to significantly boost their potency. These proteins are considered a potential source for developing new treatments to combat antibiotic resistance, although their application as drugs requires further research due to their limited stability within the body.
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