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Japan has begun a trial of a pioneering treatment for Parkinson’s disease involving the transplantation of induced pluripotent stem cells that develop into dopamine-producing brain cells. The first procedure was performed at Kyoto University Hospital in October, following conditional regulatory approval in March. In a trial involving seven patients aged 50 to 69, participants received 5 million or 10 million cells on both sides of the brain. No serious side effects were recorded, and the symptoms of four patients improved after two years of follow-up. The company plans to treat 20 to 30 patients by March 2029. The treatment could receive full approval in Japan if its safety and effectiveness are confirmed over the next seven years.
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