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Influenza is spreading early this year, and the H1N1 strain is dominant. But an early start does not necessarily mean the season will be severe. Preliminary laboratory data point to a mutation that may help the virus evade antibodies in adolescents and young adults, potentially making them more susceptible to infection than in previous seasons. Experts link this to immune imprinting: many in these age groups were first exposed to the H1N1 strain in 2009, and their antibodies target a region affected by the new mutation.
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