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A new approach to measure cellular aging
Fritz Lipman Institute scientists have discovered an unprecedented mechanism of mitochondrial aging, where levels of phosphatidylcholine in cells decline with age, leading to deterioration of mitochondrial functions and their flexibility. Studies have shown that boosting this molecule through nutrition can restore mitochondrial vitality and slow cellular aging. A decrease in phosphatidylcholine levels has been observed in patients with diabetes and obesity, and is linked to faster walking speed and better memory. It has also been noted that its deficiency accelerates in women approaching menopause, which may explain the decreased energy levels in women during that stage.
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