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سرايا الإخبارية
Experimental drug shows heart protection in Duchenne
A research study from the University of Florida College of Medicine, specifically from "Health Morsani," has identified a promising treatment approach aimed at protecting the heart in patients with Duchenne muscular dystrophy. This genetic disorder causes progressive muscle weakness that also affects the heart, leading to enlargement and potential heart failure. The study demonstrated that the drug "Citanakcept," which reduces oxidative stress and targets the enzymes NOX1 and NOX4, helped improve heart functions and decreased fibrosis and inflammation in laboratory models. It has the potential to be used in the future to delay heart-related complications associated with the disease. These findings represent an important step forward in developing new treatments for Duchenne muscular dystrophy, particularly in preventing heart deterioration and reducing the risk of failure, following more than 15 years of research into the disease's mechanisms.
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