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A study published in JAMA Network Open has shown that GLP-1 medications, used to treat type 2 diabetes, reduce the risk of serious fractures among elderly diabetics, with an observed decrease of about 21% in the incidence of hip, femur, and spinal fractures over three years of use. Although physicians had feared that rapid weight loss caused by these drugs might weaken bones, the study demonstrated the opposite; however, the results do not definitively prove a direct protective effect on bones. Nonetheless, some doctors warn that these medications could be risky for patients with amyotrophic lateral sclerosis (ALS), due to their reliance on rapid weight loss, and may also lead to hair loss and increased risks of health deterioration in patients with neuromuscular disorders. Additionally, some studies suggest a decline in quality of life when using these drugs.
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