Heatstroke can be fatal even after cooling
Heatstroke is considered a serious condition that can be fatal or remain deadly even after body temperature has been reduced. It occurs when the body's internal temperature exceeds 40°C (104°F), leading to dysfunction of the brain and organs. The inflammatory activity of the immune system remains excessive for several days after the temperature returns to normal, triggering an exaggerated immune response that causes widespread inflammation and the formation of tiny clots. This damages internal organs such as the kidneys, liver, and brain. Consequently, serious complications like organ failure can occur, even with immediate cooling of the body. This risk is especially heightened in the elderly and patients with chronic illnesses, highlighting an urgent need to develop treatments that target suppression of the immune response rather than relying solely on cooling methods.
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