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Obesity drug eases apnea
Two 52-week clinical trials showed that Eli Lilly’s Foundayo pills reduced the obstructive sleep apnea index by 43.8% among patients who did not use positive airway pressure devices, and by 27.5% among those who did. The condition improved to no disease or mild disease in 31.5% and 19.6% of participants in the two groups, respectively. Participants lost about 11% of their body weight on average. The most notable side effects were gastrointestinal problems, which led some patients to stop treatment. The company plans to submit an application to the U.S. Food and Drug Administration by the end of 2026, seeking approval to use the drug to treat moderate and severe cases in adults with obesity or overweight.
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