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Alpha-gal syndrome is a food allergy caused by an immune response to the alpha-gal substance present in mammalian meats. Its symptoms appear 3 to 6 hours after consuming red meat and can include rash, swelling, digestive disturbances, and difficulty breathing. It typically develops after being bitten by certain tick species that transmit the substance. Management relies on avoiding mammalian meats, using medications as needed, and administering epinephrine for severe cases, along with measures to prevent tick bites.
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