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A recent study has shown that immune cells linked to Alzheimer's disease are encouraged not only by cells inside the brain but also by those outside it, changing previous understanding of the disease's origin. Researchers studied genetically modified mice and found that preventing the activity of microglia cells in the lymph nodes outside the brain reduces T cell accumulation in the brain and limits neural damage, even though tau protein levels remained unchanged. The results suggest that the immune system plays a greater role in the development of Alzheimer's, and targeting microglia and T cells could offer new therapeutic strategies, though more research is needed to determine how these findings might apply to humans.
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