15 Hrs
  الكتائب اللبنانية
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الكتائب اللبنانية

2026-11-06T11:09:59.365Z

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  الكتائب اللبنانية

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15 Hrs
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Hidden source of high LDL

Hidden source of high LDL

A study published in *Nature* found that chronic exposure to dietary cholesterol activates proteins known as “Ral GTPases,” causing LDL receptors in liver cells to be broken down rather than recycled. This reduces the liver’s ability to clear LDL cholesterol from the blood, and the enzyme cathepsin A plays a role in the breakdown process. Inhibiting the enzyme may be a potential therapeutic target, but its effectiveness and safety in humans have not yet been established and require further research and clinical trials.

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