18 Hrs
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التيار الوطني الحر
Source: التيار الوطني الحر
18 Hrsالتيار الوطني الحر
Source: التيار الوطني الحر
18 HrsReady to play
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A study published in *Nature* found that chronic exposure to dietary cholesterol activates Ral GTPase proteins and disrupts the recycling of LDL receptors in liver cells. This leads to the receptors’ degradation and reduces the liver’s ability to remove “bad” cholesterol from the blood. The enzyme cathepsin A contributes to the breakdown of these receptors, making it a potential target for future treatments. However, the effectiveness and safety of inhibiting it in humans have not yet been established. Elevated LDL is associated with around 3.6 million deaths each year.
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