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Scientists develop mechanical mechanism to break down bacterial defenses without antibiotics
An international team of researchers led by the University of California, San Diego, and Pompeo Fabra University has identified a new mechanical mechanism that helps bacteria break down the protective biofilms that shield them from antibiotics and the immune system. The scientists used this knowledge to dismantle bacterial communities in the laboratory without resorting to antibiotics, opening new avenues to combat the stubborn problem of antibiotic resistance. The researchers suggest that this technique relies on the production of a gel-like substance that generates mechanical pressure, pushing bacteria out of their biofilms. However, this work is still in the early stages and requires clinical trials before it can be used as an actual treatment.
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