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عين ليبيا
Smoking impacts medication effectiveness
Smoking significantly impacts how the body processes medications, as it increases the activity of liver enzymes, especially the CYP1A2 enzyme, due to compounds found in cigarette smoke. This leads to a faster metabolism of many drugs, such as psychotropic medications, chemotherapy agents, and cardiac drugs. Such changes decrease the levels of these medications in the bloodstream, often requiring dose adjustments or the selection of different drugs. The effect is more pronounced when starting or stopping smoking, necessitating careful monitoring by healthcare professionals during treatment. Additionally, smoking affects caffeine metabolism and influences the body's response to therapy, highlighting the importance of informing doctors about smoking habits to avoid unexpected side effects.
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