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A scientific study in Uganda has revealed the discovery of five mutations in the PX1 gene of the malaria parasite, which increase its resistance to key drugs like artemisinin and lumefantrine. Researchers analyzed approximately 1,500 samples collected between 2004 and 2024 and found that these mutations appeared in the middle of the first decade of the millennium and spread rapidly. They are now present in about half of the parasite strains in western and eastern Uganda. Scientists confirmed that the expansion of drug resistance could reduce treatment effectiveness and lead to higher infection rates, underscoring the need to develop new treatments and diagnostic methods to combat this growing resistance.
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