Orange Cats' Secret Unveiled After 60 Years
Two scientific teams successfully uncovered the genetic cause behind the orange fur color in cats, after more than 60 years of inquiry. The study showed that deleting a segment of DNA in a non-protein-coding region affects the activity of the Arhgap36 gene, leading to the appearance of the orange color. The researchers concluded that this genetic change increases the production of the associated RNA by up to 13 times, resulting in the creation of red and orange pigments. Additionally, the mutation is located on the X chromosome, which explains the differences in fur color between males and females, and provides new insights into the mechanisms behind color differentiation in domestic cats.
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