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Palestinian researcher Ismail Fakhida developed a new statistical framework called “FWKC” to help researchers assess agreement between diagnostic tests and a medical reference standard, particularly in studies with small or imbalanced samples. In a simulation involving samples of 30 cases, one method in the framework achieved a mean confidence-interval coverage of 97.7%, compared with 91.8% for the mathematical transformation method and 89.2% for the Wald method, but produced wider intervals. This percentage does not represent the diagnostic accuracy of the tests. The study was published in *BMC Medical Research Methodology* in October 2026. Its findings recommend choosing a statistical method according to the nature of the data, while noting the need for independent validation and broader applications.
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