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Researchers from the University of California, Southern, have discovered a small protein within the mitochondrial genome called MENTSH, which may partially explain the causes of Type 2 diabetes and offers prospects for more precise treatments. Studies have shown that a genetic variation affecting the production of this protein is linked to an increased risk of diabetes and enhances cellular response to insulin. Experiments also demonstrated that modified versions of the protein contributed to reducing weight gain in mice on a high-fat diet, marking an important step toward developing effective treatments for diabetes and obesity in the future.
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