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A team of Australian scientists has developed a new technique for delivering cancer drugs directly to brain tumors, aiming to bypass the blood-brain barrier that makes it difficult for many medications to reach brain tissue. The technique relies on using small molecules attached to parts of antibodies to enhance the crossing of drugs through the barrier and achieve more effective targeting of tumors, especially high-grade gliomas such as glioblastoma and brain tumors in children. The project, funded by the Australian government with 18.8 million dollars, seeks to re-develop drugs that previously had limited efficacy, with the goal of entering clinical trials in the coming years. The technology is still in the research and development stage and has not yet been introduced for direct treatment, but it represents an important step toward developing more precise and effective therapies for brain tumors.
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