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A recent study has shown that long-term use of melatonin supplements for treating insomnia may be associated with an increased risk of heart failure by up to 90%, along with higher rates of hospital admissions and deaths due to cardiac or overall causes. Researchers analyzed data from over 130,000 adults suffering from insomnia and found that those who used melatonin for at least a year were more likely to develop heart failure compared to those who did not use it. Although the study suggests a potential link, it does not prove that melatonin causes heart failure, and further studies are recommended to confirm the relationship.
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