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A broad genetic study has revealed that a rare mutation in the EGFR T790M gene increases the risk of lung cancer by 25 times among non-smokers, reaching up to 60 times in those who have never smoked, with a roughly tenfold increase among smokers. The study, which analyzed data from over 3.3 million individuals, indicates that genetic factors could be relied upon to identify and diagnose those most at risk of the disease, moving beyond the traditional reliance on smoking history. These findings could change the methods used for lung cancer screening and assist in early detection, particularly among non-smokers who carry this genetic mutation.
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