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A normal eye exam—or months without symptoms—does not rule out the possibility of later developing the rare optic neuropathy that may be associated with GLP-1 drugs used for weight loss and diabetes. The U.S. Food and Drug Administration has required manufacturers to add a warning to the medication information: an analysis of 126 trials recorded 6.4 cases per 100,000 person-years among people taking these drugs, compared with 3.8 cases in comparison groups. No test can predict the condition, and there is no evidence that switching medications reduces the risk. Do not change your medication without consulting a doctor, and seek urgent medical evaluation if you experience sudden vision loss or blind spots.
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