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Studies indicate that the hormone melatonin, commonly used to treat insomnia, may also help alleviate chronic muscle and bone pain. Analysis of data from 23 randomized trials involving over two thousand patients showed that melatonin reduced pain by approximately nine points on a 0 to 100 scale, achieving a level of effectiveness comparable to common pain relievers such as non-steroidal anti-inflammatory drugs (NSAIDs). The results also revealed that its effectiveness was particularly evident in patients suffering from lower back pain, arthritis, and fibromyalgia, but it did not show benefits for those recovering from painful surgeries. It is recommended to use melatonin under medical supervision as an adjunct to traditional medications.
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