New protein may indicate brain damage
A team of scientists at the Sanford Burnham Biomedical Research Institute in California has discovered a natural protein called SORLA that could help treat Alzheimer's disease in a way that reverses the brain damage it causes, rather than just slowing its progression. The study showed that increasing levels of this protein significantly reduced the accumulation of toxic tau protein tangles, which cause nerve cell damage and lead to memory decline and brain shrinkage. Although SORLA was previously known for its role in reducing the buildup of beta-amyloid protein, its effect on tau protein was not clear until now. Experiments on genetically modified mice demonstrated that elevating SORLA levels decreases nerve cell destruction and brain atrophy, offering hope for developing new treatments to reverse the damage caused by Alzheimer's in the future.
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