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Researchers at Sechenov University in Russia have developed three-dimensional cellular units based on human gum cells and tooth pulp cells, aiming to regenerate the complex supporting tissues of the teeth, which include the gums, ligaments, and bone—working together to anchor the teeth in the jaw. Experiments have shown that combining these cells promotes self-organization and achieves a balance between mechanical and biological properties, with pulp cells excelling in forming dense, strong structures, while gum cells contribute to soft tissue repair and healing. Although this research is still in development and not yet ready for clinical use, it represents an important step toward creating bioprinted tissues that can be customized to meet patients’ needs, with ongoing efforts to integrate these units into engineered structures that mimic the natural architecture of the tooth-supporting tissues.
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