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A study at New York University Abu Dhabi has found that a gene associated with cancer can elicit diverse cellular responses, with some helping to prevent tumor formation while others contribute to its development. The research showed that this gene stimulates different types of cellular aging, which serve as natural defense mechanisms to inhibit the proliferation of damaged cells, thereby reducing the risk of cancer. The scientists clarified that some cells enter a state of senescence that blocks tumor growth, whereas others can recover their ability to divide, which may facilitate disease progression. The effects of chemotherapy treatments on pre-cancerous cells were also tested, with results indicating that some drugs, such as Sinolitic compound, are effective in targeting and removing certain of these cells. This offers hope for improving cancer treatment strategies by focusing on cells that enter senescence.
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