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The American Cancer Society has added blood testing to the options for colorectal cancer screening for the first time, aiming to expand screening methods and reduce the number of cases that avoid early detection—especially among younger age groups. Blood tests are considered an alternative for individuals who refuse traditional screening methods. The new guidelines recommend using the Shield blood test, developed by Guardant Health, which received approval from the U.S. Food and Drug Administration in 2024, as a supplementary option for screening adults aged 45 to 75 at average risk. This is alongside other screening options such as stool tests and colonoscopy, to promote early detection and decrease mortality rates from the disease. These updates are significant given the rising incidence of colorectal cancer among young people and the low participation rates in conventional screening.
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