Cancer cells evade and recur

A recent study reveals that malignant tumor cells do not divide continuously; instead, they enter a dormant state of up to 7.2%, enabling them to survive chemotherapy and later reactivate to facilitate tumor regrowth. These resistant cells are inherently resistant to treatment from the start and are often surrounded by macrophages and fibroblasts, which hinder the access of drugs and immune cells to them. The researchers suggest that future therapies should target both the active and dormant regions within the tumor, noting that a higher number of dormant cells might actually be a positive indicator of extended survival without relapse.

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