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The U.S. Food and Drug Administration has warned of a possible association between GLP-1 drugs used for weight loss and diabetes—such as Ozempic, Wegovy, and Mounjaro—and a rare optic nerve disorder that may cause sudden, permanent vision loss, though a direct causal link has not yet been established. In data covering more than 134,000 participants across 126 trials, 15 possible cases were recorded, including 10 among people taking the drugs. The estimated rate was 6.4 cases per 100,000 people per year, compared with 3.8 in the comparison groups. The condition may involve a sudden, painless decline or blurring of vision and blind spots. Anyone experiencing a sudden change in vision should seek urgent medical care and should not stop prescribed treatment without consulting a doctor.
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