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A clinical study demonstrated that optogenetics, a gene therapy approach that uses light to control genetically modified nerve cells, was able to improve light sensitivity in 6 out of 10 patients suffering from advanced retinitis pigmentosa, a hereditary disease that leads to the degeneration of light-sensitive cells in the retina and progressive vision loss. Thanks to this treatment, some patients were able to detect objects in front of them and identify their locations, although the therapy does not fully restore normal vision. It remains in early stages of development and requires additional studies to improve outcomes and achieve permanent vision restoration. The researchers received the Nobel Prize in Medicine in 2026 for their discovery of the optogenetics technique, which opens new horizons for treating degenerative genetic diseases.
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