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الصحة والعلوم الشرق الأوسط
Protein cleaning gene defect linked to early neurological issues
Scientists have revealed a genetic defect in the PSMF1 gene that affects the brain's protein cleaning system, leading to the accumulation of harmful proteins and the development of serious neurological disorders, including degenerative diseases such as Alzheimer's and Parkinson's. This defect results in the deterioration of synaptic functions and nerve damage, and is associated with conditions that appear during infancy as well as the development of diseases in adulthood. This discovery offers an opportunity to develop treatments aimed at enhancing the protein cleaning system before accumulation occurs, opening new horizons in the fight against neurological diseases and improving brain health.
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