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الصحة والعلوم الشرق الأوسط
Single gene therapy lowers cholesterol for a year
A recent scientific study has shown that a gene-editing-based treatment can significantly lower cholesterol levels. A single dose resulted in a reduction of harmful cholesterol and triglycerides by up to 50%, with effects lasting for a year in patients who received the highest dosage. The study involved 15 patients and focused on a technique that uses fat bubbles containing nanometer-scale particles to track and disable the "ANGPTL3" gene, which is responsible for cholesterol metabolism and helps reduce the risk of heart disease when non-functioning copies are present. The results suggest the potential for a one-time treatment that can sustainably lower cholesterol levels, though it is important to note that the research is still in its early stages and further studies are needed to ensure safety before any widespread application.
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