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A study published in 2022 examined the relationship between excessive consumption of hot peppers and an increased risk of esophageal cancer. The analysis of 14 observational studies involving more than 11,000 participants found that those who ate large quantities of hot peppers were about three times more likely to develop esophageal cancer compared to those who ate less. This association is linked to capsaicin, the active compound in hot peppers, which may cause repeated irritation of the esophageal lining. However, experts emphasize that these results do not prove that hot peppers directly cause cancer, and moderate consumption is recommended—especially for individuals suffering from acid reflux or Barrett's esophagus. The findings call for further research to fully understand the relationship.
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