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A study in mice with a model of Rett syndrome found that daily stimulation of the brain’s fornix for two weeks restored learning and memory to normal levels and boosted the production of new neurons. When this production was halted, the improvement in memory disappeared. The researchers identified the KCC2 protein as an important molecular pathway: activating it mimicked the effects of stimulation and improved memory performance. They stressed that the findings are limited to mice and that further studies are needed before the approach can be safely applied to humans.
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