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A study published in Neurology Open Access has shown that a vitamin D deficiency in middle age may increase the likelihood of developing Alzheimer's disease. The study observed that higher vitamin D levels are associated with lower accumulation of tau protein in the brain, particularly in regions linked to the early stages of the disease, with no apparent relationship to beta-amyloid protein. The research suggests that vitamin D deficiency could be an modifiable risk factor contributing to early neural changes, although it did not establish that preventive supplements can protect against dementia. The authors call for further research to confirm these findings.
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