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Sharjah24
New discovery benefits pancreas protection
A joint American research team from the Sanford Burnham Prebys Institute and the University of Michigan has made a discovery that explains how insulin-producing pancreatic cells rely on a group of helper proteins to maintain efficient hormone production, especially during the pre-diabetic stage. The research revealed that the process of protein folding inside the cells is akin to origami art and begins to malfunction as the disease progresses. This leads to the accumulation of misfolded proteins known as "improperly folded proinsulin," which damages the beta cells responsible for regulating blood sugar levels. This discovery aims to develop new therapeutic strategies to protect pancreatic cells and slow their deterioration as diabetes advances, highlighting the importance of understanding the interaction of helper proteins to promote the health of insulin-producing cells.
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